EbeneInfo – AU – This drug may prevent severe symptoms of COVID-19 and hospitalization

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The novel coronavirus, the virus responsible for the ongoing pandemic, affects different people in different ways While most infected people develop mild to moderate illness and recover without hospitalization, COVID-19 causes more severe symptoms in some patients Doctors also warn that a person may have mild symptoms for a few days, then quickly escalate into severe, life-threatening symptoms How to avoid severe symptoms of COVID-19 and hospitalization? Fluvoxamine, an antidepressant, could help, suggest researchers at Washington University School of Medicine Read also – COVID-19 live updates: India cases climb to 87,73,479 as death toll reaches 1,29,188

Fluvoxamine belongs to a class of drugs called selective serotonin reuptake inhibitors (SSRIs) which interact with sigma-1 protein in the body and help reduce inflammation It is typically used to treat anxiety, depression and obsessive-compulsive disorder (OCD) This drug has been shown to help reduce inflammation and sepsis in animals by blocking IL-6, a pro-inflammatory cytokine Read also – Mass vaccination in India by December? IBS aims to prepare 100 million doses of AstraZeneca vaccine

Unregulated inflammation and cytokine storms (a severe immune response in which the body releases too many cytokines into the blood too quickly) are believed to be possible causes of death in patients with severe COVID-19 Read also – COVID-19 could pose a ‘health risk’ for people who are not even born yet

Researchers at the University of Washington conducted a randomized clinical trial that included 152 COVID-19 outpatients (those trying to recover at home) with mild to moderate illness in the metro St. Louis area All patients with an average age of 46 were confirmed to have COVID-19 between April 10 and August 5, 2020 They all had an oxygen saturation of at least 92% or more

As part of the trial, one group (80 patients) received 100 g of fluvoxamine and another group (72 patients) placebo three times a day for 15 days Interestingly, none of the participants in the fluvoxamine group ‘reported clinical deterioration, while six of 72 patients in the placebo group showed deterioration in symptoms

The results, which were published in the journal JAMA, suggest that fluvoxamine may be effective in preventing severe COVID-19 symptoms and hospitalization.However, the authors warned that more and more studies are being needed to confirm these results They plan to start large-scale studies soon and include patients from across the country

In the absence of a cure or vaccine, scientists tested the effectiveness of existing drugs on COVID-19 patients Favipiravir (originally designed to treat Japanese flu) and remdesivir (developed to fight Ebola) have been allowed to treat COVID-19 patients under emergency use authorization in some countries, including India

Steroids like dexamethasone, anti-inflammatory aspirin, and the antidepressant drug duloxetine are also known to be effective in managing COVID-19

Symptoms of COVID-19 may vary from person to person, and some people infected with the virus may not have any symptoms The most common symptoms are fever, body aches, dry cough, fatigue, chills, headache, sore throat, loss of appetite, and loss of smell Some people may experience more serious symptoms like a high fever, severe cough, and shortness of breath, which often indicate pneumonia and require hospitalization.

Some people with COVID-19 also have neurological, gastrointestinal (GI) symptoms, or both Neurological symptoms seen in patients with COVID-19 include loss of smell and taste, muscle weakness , tingling or numbness in the hands and feet, dizziness, confusion, delirium, seizures and stroke People infected with the new coronavirus have also reported gastrointestinal (GI) symptoms, such as loss of appetite, nausea, vomiting, diarrhea, and abdominal pain or discomfort. These symptoms can occur with or without respiratory symptoms

Seniors and people with certain underlying medical conditions are at increased risk of severe COVID-19 That said, the virus can also make young people sick enough to require hospitalization

Therefore, people of all ages should take preventative health measures such as frequent hand washing, physical distancing, and wearing a mask when going out in public. Not only will it help you protect, but also reduce the risk of spreading the infection to others

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EbeneInfo – AU – This drug may prevent severe symptoms of COVID-19 and hospitalization

Source: https://www.thehealthsite.com/news/covid-19-treatment-antidepressant-drug-fluvoxamine-may-prevent-hospitalisation-780552/

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